💊Tesofensine | 500mcg X 100

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TESOFENSINE PILLS

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Unit Size	500 mcg/pill
Unit Quantity	100 Pills
Appearance	Pills
Peptide Purity	>99.1%

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Tesofensine is a potent triple monoamine reuptake inhibitor that primarily targets the dopamine (DA), norepinephrine (NE), and serotonin (5-HT) transporters, leading to increased extracellular concentrations of these neurotransmitters in the synaptic cleft. Originally investigated for neurodegenerative diseases such as Parkinson’s and Alzheimer’s, it gained attention for its significant appetite-suppressing effects, making it a candidate for obesity treatment. By preventing the reuptake of these key neurotransmitters, tesofensine enhances dopaminergic and noradrenergic signaling, leading to increased energy expenditure, reduced caloric intake, and improved metabolic regulation.

Unlike traditional stimulants that primarily target dopamine, tesofensine’s triple reuptake mechanism results in a more sustained and balanced effect on appetite control and mood stabilization. It exerts its effects primarily in the hypothalamus, the brain’s central hub for appetite and energy homeostasis, reducing hunger signals while simultaneously increasing motivation and energy levels. Its pharmacological profile places it in a unique category distinct from traditional appetite suppressants like phentermine, which primarily target norepinephrine alone. Clinical studies have demonstrated its significant efficacy in weight loss, often exceeding that of GLP-1 receptor agonists like semaglutide, making it an exciting prospect for future obesity treatments.